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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0f6118565b94278db27550bdbfe5a0cc2ec315ec5253989dad1516dc83e1bcc' 
  AND token = 'h40CjwarAFVxZf/ditkUwHK9ZOA3PRl9RLGcu41tyO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}