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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b10004616cce4c390aea2c49ec84deb43da459b9c4e0cad5a12f8323d86f11d6' 
  AND token = 'JTS2+36kqdRaW0vexDjFBnEfUJF92+x2ysFDUOyUWbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}