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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03ea05a1ce01f40d5e526baa303127998f78206a6121273a49461602bb8f60ad' 
  AND token = '9xiolPq2gUZgNA4oZlp8LOr0hZ5dMIR9H0iiPXcxu4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}