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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5639a91ded79ce0ed3563d1adf68c2475d740a67d8d9d0a1dce87cf5ae62c011' 
  AND token = 'tOCj5bx/zwc+zL9v9rrm3bme5ItbJ7mcFyTQm47rzVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}