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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05681631ed4d8c41590a85011de37b98de15a9836ad56025a161647ec1c4bdbd' 
  AND token = 'ybn3tuj63eHZAYC+et3fMhsvIpS5LmsYV4X/N76s4Ok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}