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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e646f8d0aee0f30ddfca453cdb15c762002ff588c98bde3da88ffab37a7209f' 
  AND token = 'krIv8wTSw3gQDxdmsLg4NGI1GhZSp5mhzD+1z80vGEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}