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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8619cc23d40e88e5a2db0064414dae8973cd9fb5bd73b0e667932c0dee66a5b7' 
  AND token = 'xY9ZPYJ2gDpJb135e4P8GcPIld1HKHFsyMrl/VeEusg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}