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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e16b25e364b7b76e4a17ab97144d2bb21b9fa595f3bab63aa894c6f48bec6bbf' 
  AND token = 'cvCGimjffKWVD2tK10fpeQ0jzsHUZSgK2a/KDfM0Ahs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}