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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40d1081b578a7c24d5d54c324182303c32fcd64347037565c973bade48e29945' 
  AND token = 'jn672yJtem/oYKRD/WWlMqTGx7SyGvqPob22e5l490U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}