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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f5bd9b82e9bb7a0faa582ae41b6532270f6c8c6efef7e3748340502728b7575' 
  AND token = 'eJGMnJtgyYn5u52/hY1eIYVYlCnAy9wDwqP8bA/iFjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}