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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9df5980494f00f1832e4409d5a6bc07adf9fe6338771340eb03873ac875e10ac' 
  AND token = 'NLBN4x/qQ+CJp5QkgoPh0DvHE/6qS3GgR7aU+PfgLd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}