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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fe6a7a9a5759c2e4619d49807baa24f267ee79149b953f8310adfee63618178' 
  AND token = 'o4Fy7Dmt1EdhG2GnvvIIg1S3C71AxBvzNjQjmxi6oa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}