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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a02f640d08a63620d5794b3d7d4e2c6e9a9097cfd2371c10c59fcd829e0afe10' 
  AND token = 'JCwoD37QzE/8NQqRiuzRPh/QDjaeg5MUn1y0qzhzOgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}