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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ce921cc27660d97cf47a28610a63cd22efc5d2ad789be18365141c973f3458c' 
  AND token = '2hpAF8OL8Pol5XXMzdbMIIHT7ERpD2ZHedRRnJWTaPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}