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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8533b97c21f6244ead6f58c62917d95c7aa626b7e34fd276d616fc9b50c68427' 
  AND token = 'Ft4sGxcETf+uwj9lrCHH+d4bo4Np3l7ASOeGWuCr8Is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}