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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8adc46e65709cf34102a6a5368932152e7b633c99a890adee00b898a61802d50' 
  AND token = 'IeY8LBr+CyUSeGvo8C8byzNiNwVfrCNhx5rxX6fSE8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}