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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e530fdebf6702cda7947ce93b7c5a6b840256a45eeea3a8597e1e0a56a11dd0' 
  AND token = 'spFnYs3X/C0n8/CGvbUa3ZFJTQt8VfY829E/BRteGV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}