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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0169d6eafa0aa66b7a8312897e9b0f0326fc92277206c9732aacc8d8c1faf95' 
  AND token = '9m8LAs6aJ4PbhazD+0UxqdGVcxyBYcdhoBxS8q/jsFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}