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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd26a3d51b8ed2a267c4445d7d637d4d45d3bd349966b189977a1d90718f994f5' 
  AND token = '91DquYIA5gOlEHgQUi46vRvpgZa0zpXASlcM5YO3aX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}