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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40151ce9b46e87265baffb25fa655315f3e1d43dce8719e843b04748a6d8fa11' 
  AND token = 'LzJM2JGtUIBFl4VcfMIXBrFq3Et3Lf3X9rcnRBTytt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}