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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e0509c2898ca31c970015448cdc2a6e64bd0a7c049a39eea5e87f9af23e1575' 
  AND token = 'tcInQDijLUGwFUvwuzX363YZTS+iLM01M3mfl38Vw5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}