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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e01e0f485ee6d12de23cf4ff75509b9a20041d796b8270610e2b4fffbd0237e1' 
  AND token = 'z7UZ5hyuRBKnwIeB0DgYVlnfFHHuX6f9B85lIMqOEkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}