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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd909648681f7c5c53d6c5ec07c642a8b967ba209c47411c47d2d3bb0158d9067' 
  AND token = 'b5ZQb0g8x3PrXElEnycOWf2JPTIafD01p6kdVsBD8YI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}