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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1c6c2f928fb9543290108121733fc306d31842ba2a2b0164744bea8f53754fb' 
  AND token = '5w0R3+3Xablp1wcNiG2HwqO7v46ouyqynqny3mhhZqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}