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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c22903526e471158275e6abc937eee36411086d3e4fba7d24f7e888542e6dcbe' 
  AND token = '4LOErP7PDZYVCEC6k1to4F1YbnM2I0K/pLKnMjYYBGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}