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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '879582cc7c83fe4c613de695d8f9d2fe7c8540b4e8453afb8468c7c77d78e01a' 
  AND token = '5+1k+rt2Q51aDROaccO/QVDpAJO8bbMIVKdojO+D3xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}