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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a6c449e8645731cb13d3e7fe3fe8c9fd194076465ba89723b40774308ee5118' 
  AND token = '0RZZ6H4GNN0arMvN4R+TikFt83fQ8UlwoyiET1g5erc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}