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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1445b9b76a2c904ffeff7a713e8d198c399fa04cf3f5d9f9c9107ba8b3034783' 
  AND token = 'WPskxGCa9yjXvBJjaFmyDMAIqiJfDLCpVxpU7amD9GE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}