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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5f38363df940ce68a1258f9c10cdd9eb215ae130f341ddecc09c2b6c2226334' 
  AND token = 'fqCZ7U0/1RgfIp5NdSVXEItysPS33SnzkRWy1Bhepkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}