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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22cbdf965515123b8b7b4f9ec3971f7706813e950170946c07d5c82125460455' 
  AND token = '8RxEErU5ZmSzdEurCmSF/5O91kTeSKvZWsJW94ibwro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}