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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e88ab386b6a13784c238847ae207749d37f4ee814c8a360dea4812828ec5ce9' 
  AND token = 'bcdvKHY5ARD3tZ5lOIH3L8J0sYXOoL8vFVixvPXKysQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}