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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '384320342e3723410b43b00f10fa6a21d5dd6e140986accde688985779a54f5b' 
  AND token = 'o+Y4YMbEqY712YVIK8+w9zM5fm0sSF3Xr7h+BI6l/NE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}