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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfc64a9e5cf8a3a383b7dac42f57921a08fbd6707d53902d97e0032e7144f7f3' 
  AND token = 'hFS0OizMPgNzvkx/UCW3mAGFhFfcODtER9OSPwAWbKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}