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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bc7f37968f86644db21e2cd0384e0fb2f4c9ace9417ca1b1d8214550bd7d1bb' 
  AND token = '4u6YIZc+iOCYZWLhrPUAX0mMYvduLDd1bf5Ibmye5R4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}