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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c631ed68ebc1d32f0630efaff5058312a28da388802dad08cb1b6f57adbb3ff' 
  AND token = 'tJ0Vfq1777BQcTwj8GSNSzSGxeMplMlYLYRDHM8W0bM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}