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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0224ef26fe456d2f4f89e2a817a5ca7fe78fe5f5b2a5d61d0beee39ee4c1d99' 
  AND token = 'Nkyf48IzbZ3bZZlo7eeybnMYCa/Jqzimvf4wplty0bM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}