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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e7c1c0a943f50a88dc4687fe33af16c5b134bec87d07c2edb21000be828edca' 
  AND token = 'wXo7h50v1xz6Yh3Gw0GPA8cZ5lVLj03YKgllAF2VtOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}