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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7ddf65253b1a7e46ac2a40d639d6252b488de89b1bde3bf6b819442d3b7a012' 
  AND token = 'qoRCummU31l/5MjEpAkgrQetzbMRty7pwqTJ/TUw5Sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}