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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4951e8294aca3ea77a5d0de6535514ee8eece12eea04d8c0aeda7ad232fe9b3' 
  AND token = 'EgjQ3tx+4PCfookU/4zt1v5RRagtX+Rb1ap1MonnQL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}