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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e25fbe3c101486af0f1496cf15e02d60f346c8a8c3e4f590dbf60054b77d913' 
  AND token = '1lUXu9KTBTVcPi570xcA2IRW+Ua8ULs9bQWWDsqlHXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}