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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee5852346157c8b14d25f6c999b6170f7f77a4829d889dacec02a1a5b1e10650' 
  AND token = 'SzaRKKmuz90wNk8xAe6wj/kuQ0G9M2ZPTtacL57OYCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}