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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf4b8fb8245a6593996985e2c54fee94ab95570817fe55dec815cee0dfb7783c' 
  AND token = 'gE4UUlml49XyqbTsgHeqOQGjBHi2APH8wCDC2E/Hni8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}