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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28b87f21c3052da4017d16c2b58ce03e7dc8ec2a09ab5a403621b7716ec2de16' 
  AND token = 'fMfzFw3XZ681ZhieOHSeJ/9nwkXy5En6xEAlHetjwI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}