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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca6ac30e08b996e1ca379ddc6ec37fee8fd399d8703349f276787d02c04cdf98' 
  AND token = 'nBohwh8uDaZG4rRQ/V1uPWFLNs9FBwN1iWtCyngHGSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}