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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8d6893c7e50b22f6c8d1b2fbf8712e141290291e6f77890b29a253dc79d974e' 
  AND token = 'M6wPVdX7lNgLSD05C+k6O5XStLVd0MnZaIaj4jhIuto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}