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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d5db0e5400d8cac0671e84719bedcb9cfba5fc9ab0456599520ac9a77fdfc56' 
  AND token = '585CI2kWtlGcxNgorlb7uDiWkK15qKT1roKVfY9HFMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}