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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66fca602cc0c280a02fc299fd18a014f77e5460dec22d6ae8cda0a6a107ffd13' 
  AND token = 'Np21Ep+7iOkO5iyztMhaD8cwQNNe5bi5y9LWDADZ11g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}