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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '849985c84116a41663b40dd10f67cf2b16cdf417e1d686c06bcd38acc42c1eb0' 
  AND token = 'Gmqc+U+3dhs1od9ap2lMw0NgcVd9ZDQZcCZtq1ax4WQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}