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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd01b8ea2c9ccd50c77127f1e51705ecbae07d40a4b9138c3c296ef329ba48497' 
  AND token = 'rp20Ong+Rs35d6A5g/7RHQKJlhStS1B+rrVsQxcHw3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}