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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79df5f84692b7d3de66be4f649063af55b703ea8eba98b7052b8ecaf746818d6' 
  AND token = 'ER3oo3pa/rKYWkXMugmo/LGhxYcbtcMdVKiziPAtYXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}